Ciprofloxacin Oral Solution 10% for Poultries Manufactured by GMP Certificated Factory

• Varieties: General Disease Prevention Medicine
• Component: Ciprofloxacin
• Type: The First Class
• Pharmacodynamic Influential Factors: Combined Medication
• Storage Method: Prevent High or LowTemperature
• Veterinary Reg. No.: (2018) Veterinary Drug Production Certificate No.
• Model NO.: Ciprofloxacin
• Specification: 100ml orcustomized
• Trademark: CHBT
• Origin: Henan China
• Production Capacity: 50000bottle/Week

Product Description

PHARMACOLOGICAL ACTIONS:
Pharmacodynamics Enrofloxacin is a broad-spectrum bactericidal agent for fluoroquinolone animals. For Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Porter's sepsis Bacteria, Staphylococcus aureus, Mycoplasma, Chlamydia, etc., have good effects, but have weak effects on Pseudomonas aeruginosa and Streptococcus, and weak effects on anaerobic bacteria. It has obvious antibacterial effect on sensitive bacteria. The antibacterial mechanism of this product is to inhibit bacterial DNA gyrase and interfere with bacterial DNA replication, transcription and repair and recombination. The bacteria cannot grow and reproduce normally and die.
Pharmacokinetics This product can be absorbed well when taken orally in most animals. The bioavailability of oral administration of chickens is 62.2% to 84%. It is widely distributed in the body of poultry and can enter tissues and body fluids (including bones). Except for cerebrospinal fluid, the drug concentration in almost all tissues is higher than that of plasma and liver metabolism. Remove the ethyl group of the 7-piperazine ring to generate ciprofloxacin, followed by oxidation and glucuronic acid binding. It is mainly excreted through the kidneys (through renal tubular secretion and glomerular filtration), and 15% to 50% is excreted in the urine in its original form. The elimination half-life of oral administration of this product in chickens is 9.1 to 14.2 hours.
DRUG INTERACTIONS:
(1) This product is used in combination with aminoglycosides or broad-spectrum penicillin, which has a synergistic effect.
(2) Heavy metal ions such as Ca2+, Mg2+, Fe3+ and Al3+ can chelate with this product and affect absorption.
(3) When combined with theophylline and caffeine, it can reduce the plasma protein binding rate, abnormally increase the concentration of theophylline and caffeine in the blood, and even cause symptoms of theophylline poisoning.
(4) This product has the effect of inhibiting liver drug enzymes, which can reduce the clearance rate of drugs mainly metabolized in the liver and increase the blood drug concentration.
INDICATIONS:
Fluoroquinolone antibacterial drugs. Used for chicken bacterial diseases and mycoplasma infections.
DOSAGE AND ADMINISTRATION:
Mixed drinking: 0.5~0.75ml for poultry per 1L of water.

 

Henan Chuangxin Biological Technology Co., Ltd. is a large joint-stock company integrating animal drug research and
development, production and sales, and after-sales service. In December 2012, the one-time high score passed the
acceptance of eight veterinary drug GMP production lines of the Ministry of Agriculture. The production dosage forms
involve powder/premix, terminally sterilized small-volume injection (including Chinese medicine extraction)/terminally
sterilized large-volume non- Intravenous injection (including traditional Chinese medicine extraction) / oral liquid solution
(including traditional Chinese medicine extraction), non-chlorine disinfectant (liquid), feed additives(Probiotics Green) and
Originally created China's leading Chinese medicine antiviral preparations, animal Chinese medicine extract preparations
such as Toad venom and Cantharidin. Known as the GMP standard model factory of veterinary drugs in Henan Province.